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Genetic factors influencing glucagon-like peptide-1 receptor sensitivity and glucose metabolism may affect both tolerability and therapeutic benefit over time

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Overweight and obesity medication efficacy increases with diet and exercise

it may reflect drug classmediated activation of other cardiovascular protective mechanisms

If levels are low, follow Diabetes UK/NHS guidance for treating hypoglycaemia by consuming 1520 grams of fast-acting carbohydrate (such as glucose tablets, fruit juice, or sugary sweets) and rechecking after 15 minutes