Thioguanine nucleotide (TGN), the active metabolite of MP disrupts DNA replication of rapidly dividing cells, such as activated T-cell lymphocytes
The body often adapts quickly, and the side effect subsides even as the protocol continues.
To view a copy of this licence, visit About this article Cite this article Li, T., Tian, Y., Zhong, Q
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A 2025 narrative review of musculoskeletal research described both the regenerative findings and the open questions about translation to human clinical use (PMID 40789979)
This compound is intended for research use only, and its applications outside of laboratory settings have not been established