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Sigal M, Rothenberg ME, Logan CY, Lee JY, Honaker RW, Cooper RL, Passarelli B, Camorlinga M, Bouley DM, Alvarez G, Nusse R, Torres J, Amieva MR (2015) Helicobacter pylori activates and expands Lgr5+ stem cells through direct colonization of the gastric glands

When GLP-1 medications are introduced, they amplify these natural effects which is why they are so effective, but also why digestive side effects are so common

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An initial formulation with a fat to protein-plus-carbohydrate ratio of 80:20 demonstrated poor acceptability among participants

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