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This paper demonstrated that decreasing glycolytic flux can cause carbons to be redirected through the PPP

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15 , eabm7524 (2022)

The only exception is canagliflozin, which causes delayed ossification of the metatarsal bones that may be attributed to effects on calcium homeostasis observed in earlier studies in healthy human adults ( Poor glycemic control in the periconception period and in pregnancy has significant maternal and perinatal risks ( As for addressing key questions remaining in regards to this topic we first suggest future studies to more thoroughly report maternal and treatment characteristics including trimester of exposure

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