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del Amo, J

34 Patients with cirrhosis of the liver have hypermethioninemia and a block of the trans-sulfuration pathway leading to delayed methionine clearance and decreased concentration of methionine endproducts (including GSH) following a methionine load

doi: 10.3389/fmolb.2023.1200025 Received 04 April 2023 Accepted 24 April 2023 Published 05 May 2023 Volume 10 - 2023 Edited by Julio Plaza-Diaz, Childrens Hospital of Eastern Ontario (CHEO), Canada Reviewed by Vijay Karkal Hegde, Texas Tech University, United States Dan Gao, Xian Jiaotong University Health Science Center, China Xiujing Feng, Shandong First Medical University, Jinan, China Updates Copyright 2023 Mohamad Ishak and Ikemoto

The reasons for the apparent peak in overdose deaths arent fully understood, but experts have a few hypotheses

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Dont take vitamin B12 supplements if you have sensitivities or allergies to vitamin B12, cobalt, and any other ingredients in the medication