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Proc Natl Acad Sci USA 1974

It is not appropriate for patients with active malignancy without oncology clearance

Most of these agents act as inhibitors to affect downstream pro-inflammatory cytokines by blocking the corresponding targets, reducing symptoms and pain ( Figure 1 )

Targeted delivery systems that concentrate peptides at fracture sites will likely improve efficiency and reduce the need for systemic exposure

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In models of corticosteroid-impaired muscle healing, BPC-157 completely reverses the aggravating effects of systemic corticosteroid treatment (6-methylprednisolone), restoring normal healing kinetics and full functional recovery