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Daily intraperitoneal injections of GGsTop, which has previously been shown not to impair tumour growth 47 , did not abolish kidney GGT activity (Extended Data Fig

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A way to explain cell death associated with reduced levels of GSH is ferroptosis, a unique iron-dependent form of non-apoptotic cell death, characterized by lipid peroxidation with ROS accumulation due to GSH peroxidase inactivation and high levels of GSH consumption

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Peptides break down in the gut, so the sublingual route is preferred for consistent systemic delivery without the need for injection