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To induce depressive-like behavior, 5 out of 11 of the studies used an inflammatory depression induction protocol through the intraperitoneal administration of LPS (lipopolysaccharide) [32,33,34,35,36] (Table 2) with LPS doses ranging from [36], 0.5 mg.kg -1 [35], 0.83 mg.kg -1 [32, 33, 36], and 1.5 mg.kg -1 [34]

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The lives of some users have been irreversibly adversely affected