The SIKis have yet to be tested on whole humans (not just loose patches of skin) to check for the effects of the drug leaking into the rest of the body, or discomfort from the drugs action on the skin
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Thus, they are able to modify all biological macromolecules including lipids, proteins, RNA and DNA, and impair their function
Epidemiological data also suggest that paternally derived genetic damage may contribute significantly to the aetiology of cancer in children and young adults [1, 2]
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