and Clark et al
As IC/BPS might be multifactorial, future research should target different implicated pathways simultaneously and study the role of reactive oxygen species as a root cause in IC/BPS
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Food and Drug Administration (FDA) DailyMed Label: Bacteriostatic Water for Injection (Provides official labeling, storage instructions, and preservative information) United States Pharmacopeia (USP) USPNF General Chapters & Monographs (Defines standards for sterile water for injection and pharmaceutical quality requirements) World Health Organization (WHO) WHO Good Storage and Distribution Practices (Guidelines for temperature control, sterility, and pharmaceutical handling) American Society of Health-System Pharmacists (ASHP) (Clinical guidance on sterile product handling and multi-dose vial use) FDA Guidance on Sterile Drug Products (Aseptic handling, contamination risk, and storage principles)
As a result of the action of these substances, the cells became more susceptible to BCL-2 family inhibitors, especially the compound ABT-263, which has proven senolytic properties [135]
