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After accounting for the results from the interim analysis, the nominal two-sided significance level for the primary outcome was 0.04561

Research has shown that most (if not all) of the lean tissue lost during weight loss may be non-fat lean tissues (like water) found in our fat cells (adipose tissue)

For people who are sensitive to GI side effects, slower titration generally produces better tolerability

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While this exceeds room temperature storage recommendations for unopened medication, its sufficient for opened pens within their room-temperature window