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In animal models, it has been shown to reduce amyloid plaques and hyperphosphorylated tau, key pathologies in Alzheimer's disease

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The biofilm was affected by both peptides in a dose-dependent manner, although M4 concentrations above 12.5 M caused a strongly increased membrane permeabilization, while for M3 it was observed at concentrations above 50 M

The dissected pancreata were subsequently washed in RPMI-1640 medium prior to islet separation using a gradient with Histopaque-1119 and -1083 (both from Sigma Aldrich)

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