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And GLP-1 can inhibite hepatocyte apoptosis which induced by NLRP3 through autophagy in mitochondria, weakening the intrahepatic inflammatory response, thereby inhibiting the transition from simple fatty liver to nonalcoholic steatohepatitis (NASH)

Six weeks of HF-SAAR feeding improved insulin tolerance similarly in WT and KO mice compared to HF-CTRL groups (Fig

Several critical enzymes that require ascorbate as a cofactor include the collagen processing enzymes, the lysyl hydroxylases and the prolyl hydroxylases as well as the catecholamine synthesis enzyme dopamine -hydroxylase

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