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Addressing these factors optimizes peptide effectiveness

The resulting HSA-Mn 3 O 4 and HSA-TI are then cross-linked via ROS-cleavable thioketal linkers and covalently immobilized onto platelet, forming the platelet-nano assemblies 55

563 Monitoring and considerations include dose titration, initiating medications at low doses and gradually increasing to the maximum tolerated dose while monitoring efficacy and adverse effects