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doi: 10.3390/ijerph19010137 32 HiluyJCNazarBPGonalvesWSCoutinhoWAppolinarioJC

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The cAMP signaling pathway potentially enhances melanin production and deposition, which serves as a natural defense against UV penetration and facilitates nucleotide excision repair (NER), a crucial process for potentially removing UV-induced DNA lesions and averting mutagenesis

Treatment for genuine hypercortisolism depends on the underlying cause and may involve medication, surgery, or radiotherapy

It achieves this by modulating various inflammatory cytokines and growth factors, creating a more conducive environment for healing and minimizing the factors that contribute to abnormal scar formation

This scenario is frequently misinterpreted