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Researchers prevent this by immediately deproteinizing samples with acidic solutions such as metaphosphoric acid (MPA) or perchloric acid (PCA) and processing all materials on ice

Lab-technical guidance for the researcher handling the material

This measured approach allows care to remain calm, thoughtful, and aligned with overall well-being

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Knock-down of states within the cell can be directly incorporated into the dynamic modeling framework by adjusting the protein production rates of Nrf2, Keap1 and p62 for the corresponding knock-downs