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J Clin Investig 123(6):27302736

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Of the many possible modifications tested in our preliminary studies, two stand out chemical modifications used for enhancing peptide bioavailability were found to change the stereochemistry of its amino acid constituents and N- methylation [21,22]

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To view or add a comment, sign in New Research Insight | Therapeutic Strategies for Ethanol-Induced Gastric Ulcers Gastric ulcer (GU) remains a significant health concern, commonly associated with alcohol consumption, smoking, and physiological stress

[24] [25] Both hormones are rapidly degraded by the enzyme dipeptidyl peptidase-4 (DPP-4), resulting in half-lives of approximately 5-7 minutes for GIP and 1-2 minutes for native GLP-1