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Given the partial-agonist, Gs-biased profile, functional characterization should distinguish cAMP/Gs signaling from -arrestin recruitment rather than collapsing them into a single activity readout

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GLP-1 and the Brain: How These Drugs Might Affect Mood and Reward Originally, GLP-1 drugs were valued for their effects on the pancreas and gut, but we now know GLP-1 receptors are also found in the brain