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This reaction is reversible

GLUTATHIONE AS AN ANTIOXIDANT Oxygen radical stress occurs in all aerobic organisms as a result of aerobic metabolism, with intermediates such as superoxide and hydrogen peroxide that lead to further production of oxygen radicals, which can cause lipid peroxidation and disrupt metabolic processes

Therefore, while GLP-1RAs may represent a promising therapeutic option for managing psoriasis, further high-quality studies are needed to distinguish whether the therapeutic effects of GLP-1RAs originate from the direct regulation of immune cells or improvements in comorbidities such as obesity or diabetes

In our previous study, the decrease in eGFR was slower in patients treated with SGLT2i than in those treated with GLP1Ra during monotherapy ( Another possible mechanism may be the difference in the mean BP at the time of drug treatment