muscle weakness semaglutide Glucagon-like peptide-1 receptor agonists and mass effects An Important Reminder When Taking

Immediate medical attention is required if thirst is accompanied by any of the following: Severe or persistent vomiting or diarrhoea leading to inability to maintain hydration Signs of dehydration such as dizziness, reduced urine output, dark-coloured urine, or dry mucous membranes Symptoms suggestive of hypoglycaemia (blood glucose below 4 mmol/L) that do not resolve with standard treatment Severe abdominal pain, which may indicate pancreatitisa rare but serious adverse effect of GLP-1 receptor agonists Symptoms of DKA, including rapid breathing, fruity breath odour, confusion, or loss of consciousness If pancreatitis is suspected (severe, persistent abdominal pain, possibly radiating to the back), stop taking semaglutide and seek urgent medical assessment

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This guide is intended for use by patients and their healthcare providers

Acknowledgements The study was funded by a European Research Council advanced grant (ElectroGene, No

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Setting realistic and achievable goals is emphasized to foster sustained success