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At 48 weeks, 100% of participants on the 8 mg and 12 mg doses had achieved at least 5% weight loss (Jastreboff et al., NEJM , 2023)
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Cloudiness or particulate formation indicates peptide aggregation, bacterial contamination, or chemical degradationnone of which are reversible
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The nasal spray is absorbed through the nasal lining, which can result in a different onset time and intensity compared to other forms
Side effects and effectiveness can also vary depending on your own body chemistry
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