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This combination aims to simplify delivery while maintaining the functional characteristics of each component

The synthetic version was designed to replicate those regulatory effects in a stable, injectable form

Treatment of cells with SPIONs significantly reduces the expression of tumor stem cell markers (CD117, NANOG, CD133, and SOX2), cell proliferation factors (KI67, CCND), autophagy-related factors (ATG3, ATG5, MAP1ALC3a, MAP1ALC3b, and MAP1ALC3c), and some negative regulators of ferroptosis, while significantly increasing the mRNA expression levels of cell death-related proteins (BAK1 and BID) and certain positive regulators of iron dependent death

Am Surg 87(8):12871291

Some people experience severe nausea, vomiting, or other side effects that make GLP-1 injections intolerable even at low doses

References 1.Wang L., Chen W., Lin X., Zhang Z., Wang N., Lv Y., Wang X., Gao Y