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The Neh6 domain is fundamental for Nrf2 alternative degradation since it is rich in serine residues that are subjected to phosphorylation by glycogen synthase kinase-3 (GSK-3)

It is crucial for diagnosing B12 deficiency, which can arise from dietary insufficiency or underlying medical conditions

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That makes them ideal for volume eating, a strategy where you fill your plate with physically large, low-calorie foods to feel full without overeating

The test helps identify deficiency in these at-risk groups early on, reducing the likelihood of serious health issues