The thinking is that by concentrating the peptide in the inflamed or damaged areabe it the lower back near the compressed nerve root or the gluteal area for piriformis syndromeyou maximize its local effects before it enters systemic circulation
10.1016/j.bbr.2020.112919 Summary Keywords retina, ischemia, BPC 157, L-NAME, rats Citation Zlatar M, Kokot A, Vuletic LB, Masnec S, Kralj T, Perisa MM, Barisic I, Radic B, Milanovic K, Drmic D, Seiwerth S and Sikiric P (2021) BPC 157 as a Therapy for Retinal Ischemia Induced by Retrobulbar Application of L-NAME in Rats
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N-acetyl-l-cystine (NAC) protects against H9N2 swine influenza virus-induced acute lung injury
(eds) The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine