Cyanocobalamin can be converted to 5-deoxyadenosylcobalamin and methylcobalamin in the body
I experienced improved energy and reduced fatigue, particularly during periods of caloric restriction
The dosing regimen varies depending on whether neurological symptoms are present: With neurological involvement: 1 mg intramuscularly on alternate days until no further improvement, then 1 mg every 2 months [3] [4] Without neurological involvement: 1 mg intramuscularly three times a week for 2 weeks, then 1 mg every 2-3 months for maintenance [3] [4] There is some evidence that high-dose oral B12 (1000-2000 micrograms daily) may be effective even in some malabsorption conditions, though UK practice still generally favours intramuscular treatment in these cases
They are naturally occurring, biologically active, coenzyme forms of vitamin B12
The complete chemical structure of the molecule was determined by Dorothy Hodgkin based on crystallographic data and published in 1955 [147] and 1956, [148] for which, and for other crystallographic analyses, she was awarded the Nobel Prize in Chemistry in 1964
We prefer subcutaneous, because it is painless, effective, very easy to do by yourself, and carries no risk of nerve injury