While theres still research to be done on exactly how omega-3s support gut health, it appears to change the bacterial makeup of the gut microbiome to prioritize healthy bacteria and provide anti-inflammatory compounds
For instance, treatment with SGLT2 inhibitors results in a decline in long-chain acylcarnitines that parallels improvements in mitochondrial function and correlates with a slower rate of eGFR decline [168], suggesting that these metabolites can serve as sensitive pharmacodynamic biomarkers
Note that in some instances, doses higher than those used in the treatment of type 2 diabetes were chosen (for example, semaglutide 2.4 mg weekly injections)
10.1002/bit.26306 44 LouisF.KitanoS.ManoJ
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For context on how unusual this valuation is: Viking Therapeutics (VKTX) , a fellow metabolic developer, carries a market cap around $4.35 billion
