Commonly reported side effects include: Nausea, vomiting, or stomach cramps Diarrhoea or loose stools A distinctive 'fishy' body odour, caused by the production of trimethylamine a metabolic by-product of carnitine breakdown in the gut These gastrointestinal effects are more likely at higher doses, particularly above 3,000 mg per day, and are consistent with adverse effects described in the levocarnitine SmPC
Your provider monitors your response closely and will only increase your dose when your body is ready
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Furthermore, SCFAs activate GPR43, leading to blocking IB phosphorylation and degradation, which inhibits NF-B activity and reduces inflammatory gene expression ( Figure 3 ) [88]