Their primary function is to regulate glucose metabolism by stimulating insulin secretion when blood sugar is elevated, without causing excessive insulin release when levels are low
*adapted from American Diabetes Association 2024 Standards of Care in Diabetes Available GLP-1 Receptor Agonists (GLP-1 RA) The Table below compares currently available GLP-1RA formulations, notes on their dosing and administration schedule, adjustments and demonstrated cardiorenal benefits
By mimicking and amplifying these natural processes, GLP-1 receptor agonists help to reduce hunger, decrease food intake, and stabilize blood glucose levels
Experimental studies involving GHRP-6 include: Ghrelin receptor binding Increased feeding behaviour in the model Growth hormone secretion Neuroendocrine signalling Gastrointestinal hormones Because of these properties, GHRP-6 is preferred for studies involving appetite-pathway signalling alongside growth hormone secretion
While we did not test our antibodies with GLP-1 in female mice or monkeys, we know the individual components work in both genders and expect the full combination with GLP-1 in females would work similarly well
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