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4b) with similar potency but lower efficacy (~10%) than glucagon (ESM Table 4)

Stopping either therapy without making necessary lifestyle adjustments can lead to weight gain

However, their outcomes were often limited, and many were accompanied by tolerability concerns

Researchers hypothesize that by modulating the hypothalamus, GLP-1s can help normalize body temperature fluctuations, reducing the severity and frequency of hot flashes

Additionally, these peptide nasal sprays are being actively explored for their potential in mood management, cognitive improvement, and skin health

As a result, most dermatologists now consider microdermabrasion to be an outdated technique for skin lightening, preferring more advanced and targeted treatments such as chemical peels, laser therapy, or topical skincare products with proven skin lightening ingredients