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There are also trials demonstrating the important role of Lactobacillus acidophilus and Bifidobacterium bifidum in promoting the migration of MMCs and facilitating small intestinal transit, lower GI motility (77)

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A 2025 comprehensive review in IJMS describes emerging delivery strategies including lipid nanoparticle-based mRNA therapies and CRISPR-dCas9 epigenetic editing to overcome BBB obstacles