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The relative expression of genes were normalized to glyceraldehyde 3-phosphate dehydrogenase (GAPDH) expression and calculated via RQmax method

Wilkins, B

There were no significant differences between inflamed and non-inflamed intestinal mucosa in UC, but UC was significantly different from CD and non-IBD mucosal gut microbiota [133]

A signature of combination drug treatment synergy was created by selecting statically significant (adj p value 0) genes from the above comparison

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This evidence gap means some caution remains appropriate despite the favorable safety signals available