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Li nda Bethea: I've never seen a news cycle like this before
But the peptide inside has unfolded into an inactive conformation that will produce no melanocortin receptor activation regardless of dose
Once phosphorylated, HSL appears to expose more hydrophobic regions
00:15:54 Craig Williams Yeah, and I was going to add briefly that when patients do lose a lot of weight, they feel so much better that we have had a couple patients who are the motivation kind of changes to keep the weight off when they get it off, maybe as opposed to trying to lose it kind of in the 1st place
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