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GHK-CU modulates gene expression and copper metabolism

For an avascular structure like a disc, even modest improvements in surrounding blood flow could meaningfully increase nutrient delivery

Additionally, serum TNF- titers, as well as levels of additional proinflammatory cytokines, are higher in patients with IC than in control subjects

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When GSH regeneration is further limited by inhibition of SLC7A11 (with erastin), cell death ensues