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The direct downstream targets of mTORC1 are ribosomal S6 kinase (p70S6K) and eukaryotic initiation factor 4Ebinding proteins (4EBP) which regulate protein translation, cell size and cell cycle progression 7,8

NAD+, nicotinamide adenine dinucleotide

MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase

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p.A30P is the only mutant that has been found to form faster oligomers and slowed the conversion from oligomers to fibrils

Stimulated emission depletion microscopy and atomic force microscopy-based analysis revealed that this cytoskeletal adaptability facilitates the spatial compartmentalization and mechanical responsiveness of astrocytes to environmental stimuli 23