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The Osmotic Engine Model (OEM) predicts that confined cell migration is facilitated by directed water permeation driven by a gradient of aquaporins, ion transporters, and ion channels [162]

Metabolomic alterations in the blood plasma of older adults with mild cognitive impairment and Alzheimer's disease (from the Nakayama Study)

By exploiting solvent-exposed amino acid side chains on antibody frameworks, these methods enable precise control over protein orientation during conjugation, thereby facilitating the rational design of bispecific antibodies with optimized spatial arrangements for enhanced activity and stability

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