Skrede et al., 2004
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Recent studies demonstrate that curcumin significantly downregulates miR-21 (oncomiR suppression) while upregulating miR-34a/b/c by two- to four-fold in colorectal cancer cells ( p = 0.002), miR-138 ( p = 0.024), and miR-16 ( p = 0.0001) in human subjects, demonstrating systemic miRNA modulation ( Resveratrol targets the miR-200 family and miR-125b-5p for epithelialmesenchymal transition (EMT) inhibition
PMID: 28340339 Zhang C, Xie Y, Chen H, et al
This document contains vital information about potential side effects, interactions with other medications, and guidelines for usage