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10.1016/j.neuint.2011.04.004 Neurochem

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Loss of the normal lobular architecture with irregular growth pattern

In mice and rats, standard two-year carcinogenicity studies with insulin glargine were performed at doses up to 0.455 mg/kg, which was for the rat approximately 65 times the recommended human subcutaneous starting dosage of 0.2 units/kg/day (0.007 mg/kg/day) on a mg/kg basis

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The Mysterious Motivational Functions of Mesolimbic Dopamine