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The pharmacology of the native IGF-1 system has been characterized in peer-reviewed studies published in the New England Journal of Medicine , Endocrine Reviews , and other top journals, and the IGF-1 LR3 analog has been characterized in the American Journal of Physiology Endocrinology and Metabolism and Drug Testing and Analysis

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Previous studies have demonstrated that IGF- 1 deficiency contributes to vascular rarefaction and impaired vasodilation in the brain [18, 21, 29, 44], yet the consequences of IGF- 1R deficiency in skeletal muscle endothelium remain unclear

Among hospitalized patients who develop acute kidney injury in the setting of rhabdomyolysis, the mortality rate ranges from 30% to 50% [2]

What I learned is that this isnt rare