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The exact cause of IBS remains incompletely understood, but contributing factors include visceral hypersensitivity (increased pain perception in the gut), altered gut motility, changes in the gut microbiome, low-grade inflammation, and psychological factors such as stress and anxiety

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The semaglutide group had increased CTX-1, with an estimated difference of 166.4 g/L (p = 0.021), and reduced BMD in the lumbar spine (ETD: -0.018 g/cm

Tsang, Y

Impact of the ALLHAT/JNC7 Dissemination Project on thiazide-type diuretic use