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Measurement of microsomal cytochrome P450 2E1 and 3A4 enzymes Cytochrome P450-dependent monooxygenase enzymes play important roles in maintaining redox homeostasis and detoxification of various drugs

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The human leukocyte antigen ( HLA-Cw6 ) is considered one of the strongest alleles determining the development of this disease (199, 207)

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