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It's used in clinical practice as a compounded peptide prescribed by physicians for tissue support and skin health
in Cancer: Phytochemistry and Pharmacological Insights
It also produces the precursors of certain amino acids and the reduced form of nicotinamide adenine dinucleotide (NADH), a cofactor for many biological reactions
Hence, a peptide was designed by substituting the negatively charged residues D42, D48, D49, E51, E56, and D57 within the p53 TAD PEP with alanine to increase its binding affinity to FOXO4 FHD and enhance membrane penetration
Composed of three amino acids cysteine, glycine, and glutamine