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Studies show FOXO4-DRI treatment reduces senescent cell burden by 50-70% in various tissues including liver, kidney, and adipose tissue within weeks of treatment initiation in aged mice

TDM received research funding from the German Research Foundation (DFG) within TRR-152 (P23) and TRR-296 and the German Center for Diabetes Research (DZD), and the European Union (ERC CoG) TRUSTED 101044445

Vitamins B2 (riboflavin), B6, B9 (folate) & B12 are interconnected in the folate cycle, the remethylation pathway and in the glutathione cycle