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Glutathione peroxidase (GSH-Px) can promote the reaction of hydrogen peroxide (H2O2) and reduced glutathione to produce H2O and oxidized glutathione (GSSG)

Calculations of key parameters of the mitochondrial function were performed, consisting of basal respiration (BR, OCR initial OCR rot/AA ), ATP production (ATP, OCR initial - OCR oligo ), proton leak (PL, OCR oligo OCR rot/AA ), maximal respiration (MR, OCR FCCP OCR rot/AA ), spare respiratory capacity (SRC, OCR FCCP - OCR initial ), spare respiratory capacity [%] (SRCP, MR/BR*100), non-mitochondrial respiration rate (NMRR, OCR rot/AA ), and coupling efficiency [%] (CE, ATP/BR*100)

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PMC 10215789

Wang J, Seebacher N, Shi H, Kan Q, Duan Z (2017) Novel strategies to prevent the development of multidrug resistance (MDR) in cancer

Blumenthal, MD, FACC, FAHA, FASPC, FNLA, and Vice Chair Pamela B