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Dose escalation should not occur in any child who has lost more than 0.5 BMI z-score units per month, given the risk of lean-mass depletion

RNA microarray and gene expression analysis An Agilent Array platform (Agilent Technologies, Santa Clara, CA, USA) was employed for microarray analysis

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Since GLP-1 antagonists slow digestion, they may worsen certain gastrointestinal conditions

33 The primary biomechanical forces that affect the ACL include axial loading, anterior tibial translation, and rotational forces

Some patients may also notice appetite variations within the weekly dosing interval, with potential increases in hunger towards the end of the week before the next dose is due