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No statistically significant pCR differences were noticed between the groups, however, the subgroup analysis showed that for HR+ patients under 40 years old, combination therapy with paclitaxel + olaparib can lead to higher pCR rates

The literature still lacks consensus on the optimal balance between sensitivity and signal stability, making cross-study interpretation difficult

Extended limitation of Gln or administration of the Gln antagonist 6-diazo-5-oxo-L-norleucine (DON) leads to growth suppression and triggers the ferroptosis pathway in PDAC

Dec 2020;170:108488

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The authors investigated the patients for changes in LH, FSH, sexual function, and quantitative changes in sperm concentration and total motile count