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Tohoku J Exp Med (2010) 221(4):28798

In vivo studies show that IGF-1 not only inhibits neuronal cell death, but also stimulates nerve regeneration in crushed or freeze-injured nerves

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Patients with certain allele combinations may have naturally heightened receptor sensitivity, meaning standard doses trigger stronger satiety and gastric effects, including nausea

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so this can be used to modify the dissolution and oral absorption of antidiabetic drugs to give high extent and release according to the physiochemical properties of the antidiabetic drugs and the onset of action needed from oral amination of drugs