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Crucial cytokines including IL-1, IL-6 and TNF- are essential for sustaining the chronic inflammatory state associated with RA [232, 233]

Researchers found that tirzepatide does not raise the risk of arrhythmias in trials

10 , e2206893 (2023)

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6a, b) Delaying G6PDi-1 treatment for 1 h post-stimulation allowed for substantial cytokine production, indicating that G6PD and the PPP likely play an important role in the early signaling events following stimulation