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Some of the ingredients used include: berberine a natural plant compound that has shown a positive effect on blood sugar levels in animal studies and may regulate cholesterol absorption in humans green tea extract high dose green tea extract has been shown to support significant weight loss, which may be due to its ability to inhibit the secretion of ghrelin, a hunger hormone Garcinia cambogia a review of 8 clinical trials found that supplementation with Garcinia cambogia resulted in an average weight loss of 1.34kg other vitamins and minerals some patches contain nutrients like chromium, cinnamon, and pomegranate Despite limited evidence that some of these ingredients may support weight loss, there is little scientific proof that their delivery through the skin via a patch is effective

Application Areas: Metabolic Disease Research: Obesity, insulin resistance, type 2 diabetes mechanism and drug development Aging and Longevity Research: NAD+ homeostasis, mitochondrial function, regulation of cell aging pathways Neuroscience Research: Exploration of protective effects on neurodegenerative diseases such as Parkinsons disease Sports Science: Enhancing endurance, promoting muscle repair and improving physical performance research

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E., & Aronne, L