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In most cases they only applied gentle pressure until the bone caved slightly inward, but in one set of experiments they purposefully cracked the skull bone, recreating a severe brain injury

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such as the polysaccharidic capsule (Nikulin et al., 2006

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The intestinal mucosa forms a critical interface between these microbes and the host: a single-cell epithelial layer with tight junctions that limit bacterial translocation, overlain by mucus and patrolled by immune cells [18]

Varga E, Nemes C, Bock I, Tancos Z, Berzsenyi S, Levay G, et al