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Phytomedicine 128, 155464

MAPK pathway Activation of the MAPK pathwaydependent inflammatory cascade has been implicated in the regulation of ferroptosis

Protopine alleviates dextran sodium sulfate-induced ulcerative colitis by improving intestinal barrier function and regulating intestinal microbiota

and widely exists in a variety of fruits, vegetables, and beverages

This raises the risk of vascular problems like atherosclerosis, heart attacks, and strokes

Acetylcysteine (also called N-Acetylcysteine or NAC) works to reduce paracetamol toxicity by supplying sulfhydryl groups (mainly in the form of glutathione, of which it is a precursor) to react with the toxic NAPQI metabolite so that it does not damage cells and can be safely excreted